Bintrafusp alfa
Bintrafusp alfa is a protein pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against programmed cell death 1 ligand 1.
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5D
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3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
57 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369—C801081—115
Lung neoplasmsD008175—C34.90482——10
Non-small-cell lung carcinomaD002289——371——8
CholangiocarcinomaD018281—C22.1131——4
Biliary tract neoplasmsD001661—C24.9—31——3
Gallbladder neoplasmsD005706EFO_0004606C23—21——2
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CarcinomaD002277—C80.026——17
Breast neoplasmsD001943EFO_0003869C5062———7
Uterine cervical neoplasmsD002583——45———6
Triple negative breast neoplasmsD064726——32———4
Neoplasm metastasisD009362EFO_0009708—44———4
Anus neoplasmsD001005EFO_0003835C2134———4
Oropharyngeal neoplasmsD009959——34———4
RecurrenceD012008——24———4
Squamous cell carcinomaD002294——23——14
Prostatic neoplasmsD011471—C6124———4
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Urogenital neoplasmsD014565EFO_0003863D071————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Esophageal neoplasmsD004938—C15————11
Esophageal squamous cell carcinomaD000077277——————11
Squamous cell neoplasmsD018307——————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBintrafusp alfa
INNbintrafusp alfa
Description
Bintrafusp alfa is a protein pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against programmed cell death 1 ligand 1.
Classification
Protein
Drug classfusion proteins
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL4298024
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDNW9K8C1JN3 (ChemIDplus, GSRS)
Target
Agency Approved
CD274
CD274
Organism
Homo sapiens
Gene name
CD274
Gene synonyms
B7H1, PDCD1L1, PDCD1LG1, PDL1
NCBI Gene ID
Protein name
programmed cell death 1 ligand 1
Protein synonyms
B7 homolog 1, B7-H1, CD274, CD274 antigen, PDCD1 ligand 1
Uniprot ID
Mouse ortholog
Cd274 (60533)
programmed cell death 1 ligand 1 (Q9EP73)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,174 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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18 adverse events reported
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