Bintrafusp alfa
Bintrafusp alfa is a protein pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against programmed cell death 1 ligand 1.
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Commercial
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Clinical
Clinical Trials
57 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 9 | 7 | 1 | — | 1 | 14 |
| Non-small-cell lung carcinoma | D002289 | — | — | 3 | 7 | 1 | — | — | 8 |
| Lung neoplasms | D008175 | — | C34.90 | 2 | 5 | 2 | — | — | 7 |
| Cholangiocarcinoma | D018281 | — | C22.1 | 1 | 3 | 1 | — | — | 4 |
| Camurati-engelmann syndrome | D003966 | Orphanet_1328 | Q78.3 | 1 | 2 | 1 | — | — | 3 |
| Biliary tract neoplasms | D001661 | — | C24.9 | — | 3 | 1 | — | — | 3 |
| Gallbladder neoplasms | D005706 | EFO_0004606 | C23 | — | 2 | 1 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 6 | 2 | — | — | — | 7 |
| Uterine cervical neoplasms | D002583 | — | — | 4 | 5 | — | — | — | 6 |
| Carcinoma | D002277 | — | C80.0 | 2 | 5 | — | — | — | 5 |
| Triple negative breast neoplasms | D064726 | — | — | 3 | 2 | — | — | — | 4 |
| Anus neoplasms | D001005 | EFO_0003835 | C21 | 3 | 4 | — | — | — | 4 |
| Oropharyngeal neoplasms | D009959 | — | — | 3 | 4 | — | — | — | 4 |
| Recurrence | D012008 | — | — | 2 | 4 | — | — | — | 4 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 3 | 3 | — | — | — | 3 |
| Squamous cell carcinoma | D002294 | — | — | 1 | 2 | — | — | 1 | 3 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 3 | 2 | — | — | — | 3 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Urogenital neoplasms | D014565 | EFO_0003863 | D07 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Esophageal neoplasms | D004938 | — | C15 | — | — | — | — | 1 | 1 |
| Squamous cell neoplasms | D018307 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Bintrafusp alfa |
| INN | bintrafusp alfa |
| Description | Bintrafusp alfa is a protein pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against programmed cell death 1 ligand 1. |
| Classification | Protein |
| Drug class | fusion proteins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4298024 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | NW9K8C1JN3 (ChemIDplus, GSRS) |
Target
Agency Approved
CD274
CD274
Alternate
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Variants
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Trends
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Safety
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Adverse Events
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18 adverse events reported
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